The Genetic and Molecular Basis of Gastrointestinal and Liver Diseases

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Slides 277 - 282 of 314 Price: $0.00
  Slide 277

Molecular Tools – DNA Sequencing

  Slide 278

DNA Sequencing 

  Slide 279

Bioinformatics

  Slide 280

Gel Electrophoresis

  Slide 281

EcoRI Genomic DNA Digestion

  Slide 282

Southern Analysis (DNA)


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Description:

This GTP unit consists of more than 314 images that review advances in molecular biology and genetics, and apply these concepts to understanding the epidemiology, pathogenesis, molecular mechanisms and treatment of gastrointestinal and liver diseases that have a defined genetic basis. Among other methods, this multimedia unit employs animated cartoons to explain complex biological phenomena and describe their relation to disease. These include signaling cascades leading to inflammation, cell proliferation and apoptosis. Specific disorders are used in the form of case histories to exemplify how hereditary and acquired genetic changes result in disease. Disorders that are considered in this context include cystic fibrosis, hemochromatosis, α-1 antitrypsin deficiency, Wilson’s disease, colon cancer, Crohn’s disease, hereditary pancreatitis and Barrett’s esophagus.

Authors:
Mark Sawicki, MD
UCLA School of Medicine
Los Angeles, CA

Stephen J. Pandol, M.D.
UCLA School of Medicine
Los Angeles, CA

James B. McGee, M.D.
University of Pittsburgh School of Medicine
Pittsburgh, PA

The authors thank Fred Gorelick, M.D., Professor of Medicine and Cell Biology, Yale University School of Medicine, New Haven, CT for providing some slides and reviewing this unit.

Artists:
Jerry Schoendorf, MAMS
Chapel Hill, NC

Stan Coffman
Medical Illustrator
Chapel Hill, NC

Mark Coffman
Medical Illustrator
Chapel Hill, NC

Release Date:

May 15, 2004